Our Abpromise guarantee covers the use of ab72247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notes
    IP: Use at 1-5µg/mg of lysate.
    WB: 1/1000 - 1/10000. Detects bands of approximately 80, 85 and 120 kDa, (predicted molecular weight of longest isoform: 91 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1.
    • Tissue specificity
      Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development.
    • Involvement in disease
      Note=Chromosomal aberrations involving BCL11A may be a cause of lymphoid malignancies. Translocation t(2;14)(p13;q32.3) causes BCL11A deregulation and amplification.
    • Sequence similarities
      Contains 6 C2H2-type zinc fingers.
    • Post-translational
      Sumoylated by SUMO1.
    • Cellular localization
      Cytoplasm. Nucleus. Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles.
    • Information by UniProt
    • Database links
    • Alternative names
      • 2810047E18Rik antibody
      • B cell CLL/lymphoma 11A (zinc finger protein) antibody
      • B cell CLL/lymphoma 11A (zinc finger protein) isoform 2 antibody
      • B-cell CLL/lymphoma 11A antibody
      • B-cell lymphoma/leukemia 11A antibody
      • BC11A_HUMAN antibody
      • BCL-11A antibody
      • BCL11A antibody
      • BCL11A B cell CLL/lymphoma 11A (zinc finger protein) isoform 1 antibody
      • BCL11A L antibody
      • BCL11A S antibody
      • BCL11A XL antibody
      • BCL11a-M antibody
      • BCL11AL antibody
      • BCL11AS antibody
      • BCL11AXL antibody
      • C2H2 type zinc finger protein antibody
      • COUP TF interacting protein 1 antibody
      • COUP-TF-interacting protein 1 antibody
      • CTIP1 antibody
      • CTIP1, mouse, homolog of antibody
      • D930021L15Rik antibody
      • Ecotropic viral integration site 9 antibody
      • Ecotropic viral integration site 9 homolog antibody
      • Ecotropic viral integration site 9 protein antibody
      • Ecotropic viral integration site 9 protein homolog antibody
      • EVI-9 antibody
      • Evi9 antibody
      • Evi9, mouse, homolog of antibody
      • FLJ10173 antibody
      • FLJ34997 antibody
      • HBFQTL5 antibody
      • KIAA1809 antibody
      • mKIAA1809 antibody
      • OTTHUMP00000159788 antibody
      • OTTHUMP00000159789 antibody
      • OTTHUMP00000201250 antibody
      • OTTHUMP00000202084 antibody
      • Zinc finger protein 856 antibody
      • ZNF856 antibody
      see all

    Anti-Ctip1 antibody images

    • Lane 1 : Anti-Ctip1 antibody (ab72247) at 1 µg/ml
      Lane 2 : Anti-Ctip1 antibody (ab72247) at 0.1 µg/ml

      Lane 1 : Nuclear extract from Raji cells
      Lane 2 : Nuclear extract from Raji cells

      Lysates/proteins at 50 µg per lane.

      Predicted band size : 91 kDa
      Observed band size : 120 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 80 kDa,85 kDa. We are unsure as to the identity of these extra bands.
    • Immunoprecipitation/ Western Blot of Ctip1.
      Lane 1: ab72247 at 1µg/0.5mg lysate for IP.
      ab72247 at 0.5µg/ml for WB.
      Nuclear lysate from Raji cells at 0.5mg for IP.
      Detection:Chemiluminescence with an exposure time of 5 minutes.

    References for Anti-Ctip1 antibody (ab72247)

    ab72247 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab72247.
    Please use the links above to contact us or submit feedback about this product.


    Sign up