The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/10000 - 1/50000. Detects a band of approximately 130 kDa (predicted molecular weight: 96 kDa).
Use at an assay dependent concentration.
Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.
Highly expressed in brain and in malignant T-cell lines derived from patients with adult T-cell leukemia/lymphoma.