Anti-CTNNAL1 antibody (ab96184)
Key features and details
- Rabbit polyclonal to CTNNAL1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CTNNAL1 antibody -
Description
Rabbit polyclonal to CTNNAL1 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment containing a sequence corresponding to a region within amino acids 292-533 of Human CTNNAL1 (NP_003789).
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Positive control
- HeLa and HepG2 whole cell lysates; SW480 xenograft; 293T and A431 lysates
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96184 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 82 kDa.
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IHC-P |
1/100 - 1/500.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 82 kDa. |
IHC-P
1/100 - 1/500. |
Target
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Function
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). -
Tissue specificity
Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland. -
Sequence similarities
Belongs to the vinculin/alpha-catenin family. -
Cellular localization
Cytoplasm > cytoskeleton. Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8727 Human
- Entrez Gene: 54366 Mouse
- Entrez Gene: 298019 Rat
- Omim: 604785 Human
- SwissProt: Q9UBT7 Human
- SwissProt: O88327 Mouse
- Unigene: 58488 Human
- Unigene: 218891 Mouse
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Alternative names
- ACRP antibody
- Alpha catenin related protein antibody
- alpha CATU antibody
see all
Images
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All lanes : Anti-CTNNAL1 antibody (ab96184) at 1/1000 dilution
Lane 1 : HeLa whole cell lysate
Lane 2 : HepG2 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 82 kDa
7.5% SDS-PAGE -
ab96184, at 1/100 dilution, staining CTNNAL1 in paraffin-embedded SW480 xenograft by Immunohistochemistry.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab96184 has been referenced in 2 publications.
- Wu D et al. CTNNAL1 participates in the regulation of mucus overproduction in HDM-induced asthma mouse model through the YAP-ROCK2 pathway. J Cell Mol Med 26:1656-1671 (2022). PubMed: 35092120
- Tan M et al. CTNNAL1 inhibits ozone-induced epithelial-mesenchymal transition in human bronchial epithelial cells. Exp Physiol 103:1157-1169 (2018). PubMed: 29791759