Overview

  • Product nameAnti-cvHSP antibody
    See all cvHSP primary antibodies
  • Description
    Mouse monoclonal to cvHSP
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein (proprietary-tag) corresponding to Human cvHSP aa 1-171.

Properties

Applications

Our Abpromise guarantee covers the use of ab57093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 µg/ml.
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Target

  • Tissue specificityIsoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.
  • Sequence similaritiesBelongs to the small heat shock protein (HSP20) family.
  • Cellular localizationCytoplasm. Nucleus. Nucleus > Cajal body. Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cardiovascular heat shock protein antibody
    • cvHsp antibody
    • DKFZp779D0968 antibody
    • FLJ32733 antibody
    • Heat shock 27kda protein family member 7 antibody
    • Heat shock protein beta 7 antibody
    • Heat shock protein beta-7 antibody
    • Hsp25 2 antibody
    • HspB7 antibody
    • HSPB7_HUMAN antibody
    • Hypothetical protein flj34956 antibody
    • RP11-5P18.6 antibody
    see all

Anti-cvHSP antibody images

  • cvHSP antibody (ab57093) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human heart.
  • Western blot against tagged recombinant protein immunogen using ab57093 cvHSP antibody at 1ug/ml. Predicted band size of immunogen is 45 kDa

References for Anti-cvHSP antibody (ab57093)

This product has been referenced in:
  • Vos MJ  et al. HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones. Hum Mol Genet 19:4677-93 (2010). WB ; Human . Read more (PubMed: 20843828) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"