The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 0.25µl for 105-8 cells. Use a final volume of 100µl.
ab18542-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
FunctionReceptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
Tissue specificityExpressed in lymphoid and neural tissues.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.