Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab8124 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General Info

  • Alternative names
    • Beta chemokine receptor-like 1
    • C X3 C CKR 1
    • C-X3-C CKR-1
    • CCRL1
    • Chemokine C X3 C motif receptor 1
    • CMK BRL 1
    • CMK-BRL-1
    • CMK-BRL1
    • CMKBLR1
    • CMKDR1
    • CX3C chemokine receptor 1
    • CX3C CKR1
    • CX3C1_HUMAN
    • CX3CR1
    • Fractalkine receptor
    • G-protein coupled receptor 13
    • GPR13
    • GPRV28
    • V28
    see all
  • FunctionReceptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
  • Tissue specificityExpressed in lymphoid and neural tissues.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt

References for CX3CR1 peptide (ab8124)

ab8124 has not yet been referenced specifically in any publications.

Product Wall

This peptide blocks the binding of the antibody -- Rabbit polyclonal to human CX3CR1 (extracellular) ab8020 -- to human CX3CR1. There is no evidence that this peptide blocks the binding of fractalkine to its receptor (i.e. binding of fractalkine to CX3...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"