CX3CR1 peptide (ab8125)
Key features and details
- Suitable for: Blocking, WB
Description
-
Product name
CX3CR1 peptide
See all CX3CR1 proteins and peptides -
Purity
95 % HPLC. -
Animal free
No -
Nature
Synthetic -
-
Sequence
DQFPESVTENFEYDDLAEAC
-
Specifications
Our Abpromise guarantee covers the use of ab8125 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
Blocking
Western blot
-
Form
Liquid -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 7.20
Preservative: 0.02% Sodium azide
Constituent: 0.1% BSA
General Info
-
Alternative names
- Beta chemokine receptor-like 1
- C X3 C CKR 1
- C-X3-C CKR-1
see all -
Function
Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. -
Tissue specificity
Expressed in lymphoid and neural tissues. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
Datasheet download
References (1)
ab8125 has been referenced in 1 publication.
- Shen F et al. Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells. Mol Cancer Res 14:518-27 (2016). PubMed: 27001765