Overview

Description

  • NatureSynthetic
  • Amino Acid Sequence
    • SequenceDQFPESVTENFEYDDLAEAC
    • Amino acids0 to 0

Specifications

Our Abpromise guarantee covers the use of ab8125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

General info

  • Alternative names
    • Beta chemokine receptor-like 1
    • C X3 C CKR 1
    • C-X3-C CKR-1
    • CCRL1
    • Chemokine C X3 C motif receptor 1
    • CMK BRL 1
    • CMK-BRL-1
    • CMK-BRL1
    • CMKBLR1
    • CMKDR1
    • CX3C chemokine receptor 1
    • CX3C CKR1
    • CX3C1_HUMAN
    • CX3CR1
    • Fractalkine Receptor
    • G-protein coupled receptor 13
    • GPR13
    • GPRV28
    • V28
    see all
  • FunctionReceptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1.
  • Tissue specificityExpressed in lymphoid and neural tissues.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Target information above from: UniProt accession P49238 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

References for CX3CR1 peptide (ab8125)

ab8125 has not yet been referenced specifically in any publications.

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Thank you for contacting us. I am happy to hear that your customer has exciting results. I suggest to include additional control to verify these results: The blocking peptide can be used to show that the antibody binds specifically. If the antibody is ...

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Application Other

Review text: Used as a control for blocking the activity of anti-CX3CR1 (ab8021) in immunohistochemistry frozen sections. Peptide was incubated with an equal volume of antibody at 37*C for 30 mins before applying to sections diluted 1:400 in PBS.
Sample: Mouse Tissue sections

Primary antibody (in addition to 'CX3CR1 peptide (Human)')
Primary antibody: Abcam primary antibody: Anti-CX3CR1 antibody (ab8021)
Dilution: 1/400

Secondary antibody
Name: Non-Abcam antibody was used: Alexa Fluor® 568 goat anti-rabbit IgG (H+L) *2 mg/
Host species: Goat
Clonality: Polyclonal
Conjugation: Alexa Fluor® 568
Dilution: 1/800
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Submitted Nov 30 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"