Overview

  • Product name
  • Description
    Chicken polyclonal to CXCL11
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Fusion protein: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLI, corresponding to amino acids 22-85 of Human CXCL11

  • Positive control
    • Prostate cancer. CXCL11 fusion protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab26946 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/3000. Predicted molecular weight: 10 kDa.

Target

  • Function
    Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
  • Tissue specificity
    High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • b R1 antibody
    • b-R1 antibody
    • Beta-R1 antibody
    • betaR1 antibody
    • C-X-C motif chemokine 11 antibody
    • Chemokine (C-X-C motif) ligand 11 antibody
    • Chemokine C-X-C motif ligand 11 antibody
    • CXC11 antibody
    • CXCL11 antibody
    • CXL11_HUMAN antibody
    • H174 antibody
    • I TAC antibody
    • I-TAC antibody
    • Interferon gamma inducible protein 9 antibody
    • Interferon gamma-inducible protein 9 antibody
    • Interferon inducible T cell alpha chemoattractant antibody
    • Interferon-inducible T-cell a chemoattractant I-TAC antibody
    • Interferon-inducible T-cell alpha chemoattractant antibody
    • IP 9 antibody
    • IP-9 antibody
    • IP9 antibody
    • ITAC antibody
    • MGC102770 antibody
    • SCYB11 antibody
    • SCYB9B antibody
    • Small inducible cytokine B11 antibody
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 11 antibody
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 9B antibody
    • Small inducible cytokine subfamily B, member 11 antibody
    • Small inducible cytokine subfamily B, member 9B antibody
    • Small-inducible cytokine B11 antibody
    see all

Images

References

ab26946 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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