Anti-CXCL14 antibody (ab36622)
Key features and details
- Rabbit polyclonal to CXCL14
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-CXCL14 antibody
See all CXCL14 primary antibodies -
Description
Rabbit polyclonal to CXCL14 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Rat, Cow, Pig -
Immunogen
Synthetic peptide corresponding to Human CXCL14 aa 1-100 conjugated to keyhole limpet haemocyanin.
(Peptide available asab36621) -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab36622 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).
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Notes |
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WB
Use a concentration of 1 µg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa). |
Target
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Function
Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactive for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. -
Tissue specificity
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes. -
Sequence similarities
Belongs to the intercrine alpha (chemokine CxC) family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 511771 Cow
- Entrez Gene: 9547 Human
- Entrez Gene: 494467 Pig
- Entrez Gene: 306748 Rat
- Omim: 604186 Human
- SwissProt: O95715 Human
- Unigene: 483444 Human
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Alternative names
- 1110031L23Rik antibody
- 1200006I23Rik antibody
- AI414372 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab36622 has been referenced in 6 publications.
- Takahashi R et al. Defining Transcriptional Signatures of Human Hair Follicle Cell States. J Invest Dermatol 140:764-773.e4 (2020). PubMed: 31676413
- Layton TB et al. Cellular census of human fibrosis defines functionally distinct stromal cell types and states. Nat Commun 11:2768 (2020). PubMed: 32488016
- Shen J et al. MicroRNA-34c promotes neuronal recovery in rats with spinal cord injury through the C-X-C motif ligand 14/Janus kinase 2/signal transducer and activator of transcription-3 axis. Chin Med J (Engl) 133:2177-2185 (2020). PubMed: 32826607
- Zeng L et al. IRX1 hypermethylation promotes heart failure by inhibiting CXCL14 expression. Cell Cycle 18:3251-3262 (2019). PubMed: 31640472
- Schüler-Toprak S et al. Agonists and knockdown of estrogen receptor ß differentially affect invasion of triple-negative breast cancer cells in vitro. BMC Cancer 16:951 (2016). PubMed: 28003019
- Strong JA et al. Microarray analysis of rat sensory ganglia after local inflammation implicates novel cytokines in pain. PLoS One 7:e40779 (2012). IHC-FoFr ; Rat . PubMed: 22815815