Overview

  • Product nameAnti-CXCL16 antibody
    See all CXCL16 primary antibodies
  • Description
    Chicken polyclonal to CXCL16
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: IHC (PFA fixed)
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 46-92 of Human CXCL16

  • Positive control
    • E.coli derived fusion protein

Properties

Applications

Our Abpromise guarantee covers the use of ab27222 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500. Predicted molecular weight: 27 kDa.

    Is unsuitable for Immunohistochemistry (PFA fixed).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
    • Tissue specificityExpressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
    • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
    • Post-translational
      modifications
      Glycosylated.
    • Cellular localizationCell membrane. Secreted. Also exists as a soluble form.
    • Information by UniProt
    • Database links
    • Alternative names
      • C-X-C motif chemokine 16 antibody
      • Chemokine (C X C motif) ligand 16 antibody
      • Chemokine, CXC motif, ligand 16 antibody
      • CXC chemokine ligand 16 antibody
      • Cxcl16 antibody
      • CXCLG16 antibody
      • CXL16_HUMAN antibody
      • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody
      • SCYB16 antibody
      • Small inducible cytokine B16 precursor antibody
      • Small-inducible cytokine B16 antibody
      • SR-PSOX antibody
      • SRPSOX antibody
      • Transmembrane chemokine CXCL16 antibody
      • UNQ2759/PRO6714 antibody
      see all

    Anti-CXCL16 antibody images

    • Anti-CXCL16 antibody (ab27222) at 1/2000 dilution + E coli derived fusion protein

      Secondary
      goat anti IgY HRP at 1/1000 dilution
      Developed using the ECL technique

      Predicted band size : 27 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)


      Exposure time : 1 hour

    References for Anti-CXCL16 antibody (ab27222)

    ab27222 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunohistochemistry (Frozen sections)
    Sample Rat Tissue sections (dorsal root ganglia)
    Specification dorsal root ganglia
    Fixative Paraformaldehyde
    Username

    Dr. Nick Jones

    Verified customer

    Submitted Mar 29 2007

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"