Overview

  • Product name
    Anti-CXCL16 antibody (Biotin)
    See all CXCL16 primary antibodies
  • Description
    Goat polyclonal to CXCL16 (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: Indirect ELISA, Sandwich ELISA, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Highly pure (>98%) recombinant full length mouse CXCL16.

Properties

  • Form
    Lyophilised:Centrifuge vial prior to opening. Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purification notes
    ab84434 is purified by affinity chromatography and then biotinylated. Filter sterilised.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84434 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA Use a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant rat and mouse protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution.
Sandwich ELISA Use a concentration of 0.25 - 1 µg/ml. Detection limit for recombinant rat and mouse protein: 0.2 - 0.4 ng/well, using 100 µl/well antibody solution. Can be used as detection antibody.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 28 kDa. Detection limit for recombinant rat and mouse protein: 1.5 - 3.0 ng/lane, under reducing or non-reducing conditions.

Target

  • Function
    Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • Tissue specificity
    Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localization
    Cell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-X-C motif chemokine 16 antibody
    • Chemokine (C X C motif) ligand 16 antibody
    • Chemokine, CXC motif, ligand 16 antibody
    • CXC chemokine ligand 16 antibody
    • Cxcl16 antibody
    • CXCLG16 antibody
    • CXL16_HUMAN antibody
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody
    • SCYB16 antibody
    • Small inducible cytokine B16 precursor antibody
    • Small-inducible cytokine B16 antibody
    • SR-PSOX antibody
    • SRPSOX antibody
    • Transmembrane chemokine CXCL16 antibody
    • UNQ2759/PRO6714 antibody
    see all

References

ab84434 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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