Overview

  • Product name
  • Description
    Rabbit polyclonal to CXCL2
  • Tested applications
    Suitable for: WB, IP, Neutralisingmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Full length protein corresponding to Rat CXCL2 aa 1-69. E.coli expressed full length protein: corresponding to amino acids 1-69 of Rat Macrophage Inflammatory Protein 2
    Sequence:

    MAPPTRQLLN AVLVLLLLLA TNHQGTGVVV ASELRCQCLT TLPRVDFKNI QSLTVTPPGP HCAQTEVIA

Properties

Applications

Our Abpromise guarantee covers the use of ab25130 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 11 kDa.
IP 1/500.
Neutralising Use at an assay dependent dilution.

Target

  • Function
    Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-X-C motif chemokine 2 antibody
    • Chemokine (C X C motif) ligand 2 antibody
    • Chemokine, CXC motif, ligand 2 antibody
    • CINC 2a antibody
    • CINC2a antibody
    • CINC3 antibody
    • CXC chemokine antibody
    • CXCL 2 antibody
    • Cxcl2 antibody
    • CXCL2_HUMAN antibody
    • Cytokine-induced neutrophil chemoattractant 3 antibody
    • GRO 2 antibody
    • GRO b antibody
    • GRO protein, beta antibody
    • Gro-beta antibody
    • GRO-beta(5-73) antibody
    • GRO-beta-T antibody
    • GRO2 antibody
    • GRO2 oncogene antibody
    • GROb antibody
    • GRObeta antibody
    • Growth regulated protein beta antibody
    • Growth-regulated protein beta antibody
    • GROX antibody
    • Hematopoietic synergistic factor antibody
    • HSF antibody
    • Macrophage inflammatory protein 2 alpha antibody
    • Macrophage inflammatory protein 2 antibody
    • Macrophage inflammatory protein 2-alpha antibody
    • Melanoma growth stimulatory activity beta antibody
    • MGSA b antibody
    • MGSA beta antibody
    • MIP 2 antibody
    • MIP 2a antibody
    • MIP2 alpha antibody
    • MIP2 antibody
    • MIP2-alpha antibody
    • MIP2A antibody
    • MIP2alpha antibody
    • SB-251353 antibody
    • SCYB 2 antibody
    • Scyb antibody
    • SCYB2 antibody
    • Small inducible cytokine subfamily B, member 2 antibody
    see all

References

This product has been referenced in:
  • Ding X  et al. TLR4 signaling induces TLR3 up-regulation in alveolar macrophages during acute lung injury. Sci Rep 7:34278 (2017). Read more (PubMed: 28198368) »
  • Han KQ  et al. Inflammatory microenvironment and expression of chemokines in hepatocellular carcinoma. World J Gastroenterol 21:4864-74 (2015). IHC-P ; Mouse . Read more (PubMed: 25944999) »

See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab25130.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up