Overview

  • Product name
  • Description
    Goat polyclonal to CXCL2
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cynomolgus monkey
  • Immunogen

    Synthetic peptide corresponding to Human CXCL2 aa 94-107 (C terminal). Synthetic peptide:

    C-KKIIEKMLKNGKSN

    , corresponding to C terminal amino acids 94-107 of Human GRO beta (NP_002080.1).
    Sequence:

    C-KKIIEKMLKNGKSN

  • Positive control
    • Human duodenum lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab91511 was purified from goat serum by ammonium sulphate precipitation, followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab91511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 11 kDa).

Target

  • Function
    Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-X-C motif chemokine 2 antibody
    • Chemokine (C X C motif) ligand 2 antibody
    • Chemokine, CXC motif, ligand 2 antibody
    • CINC 2a antibody
    • CINC2a antibody
    • CINC3 antibody
    • CXC chemokine antibody
    • CXCL 2 antibody
    • Cxcl2 antibody
    • CXCL2_HUMAN antibody
    • Cytokine-induced neutrophil chemoattractant 3 antibody
    • GRO 2 antibody
    • GRO b antibody
    • GRO protein, beta antibody
    • Gro-beta antibody
    • GRO-beta(5-73) antibody
    • GRO-beta-T antibody
    • GRO2 antibody
    • GRO2 oncogene antibody
    • GROb antibody
    • GRObeta antibody
    • Growth regulated protein beta antibody
    • Growth-regulated protein beta antibody
    • GROX antibody
    • Hematopoietic synergistic factor antibody
    • HSF antibody
    • Macrophage inflammatory protein 2 alpha antibody
    • Macrophage inflammatory protein 2 antibody
    • Macrophage inflammatory protein 2-alpha antibody
    • Melanoma growth stimulatory activity beta antibody
    • MGSA b antibody
    • MGSA beta antibody
    • MIP 2 antibody
    • MIP 2a antibody
    • MIP2 alpha antibody
    • MIP2 antibody
    • MIP2-alpha antibody
    • MIP2A antibody
    • MIP2alpha antibody
    • SB-251353 antibody
    • SCYB 2 antibody
    • Scyb antibody
    • SCYB2 antibody
    • Small inducible cytokine subfamily B, member 2 antibody
    see all

Anti-CXCL2 antibody images

  • Anti-CXCL2 antibody (ab91511) at 0.2 µg/ml + Human duodenum lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 11 kDa
    Observed band size : 17 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour


  • Predicted band size : 11 kDa
    ab91511 (0.03µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence

References for Anti-CXCL2 antibody (ab91511)

This product has been referenced in:
  • Wan XY  et al. Antimetastatic effects of norcantharidin on hepatocellular carcinoma cells by up-regulating FAM46C expression. Am J Transl Res 9:155-166 (2017). WB ; Human . Read more (PubMed: 28123642) »
  • Magni S  et al. miRNAs Affect the Expression of Innate and Adaptive Immunity Proteins in Celiac Disease. Am J Gastroenterol N/A:N/A (2014). Read more (PubMed: 25070052) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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