The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.03 - 0.1 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 11 kDa).
FunctionProduced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
Post-translational modificationsThe N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
Predicted band size : 11 kDa ab91511 (0.03µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
References for Anti-CXCL2 antibody (ab91511)
This product has been referenced in:
Wan XY et al. Antimetastatic effects of norcantharidin on hepatocellular carcinoma cells by up-regulating FAM46C expression. Am J Transl Res9:155-166 (2017).
Read more (PubMed: 28123642) »
Magni S et al. miRNAs Affect the Expression of Innate and Adaptive Immunity Proteins in Celiac Disease. Am J GastroenterolN/A:N/A (2014).
Read more (PubMed: 25070052) »