Overview

  • Product nameAnti-CXCL2 antibody
    See all CXCL2 primary antibodies
  • Description
    Rabbit polyclonal to CXCL2
  • Tested applicationsSuitable for: WB, ELISA, Neutralisingmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Highly pure (>98%) recombinant mMIP-2 (mouse Macrophage Inflammatory Protein-2)

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab9950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. To detect mMIP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mMIP-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
ELISA Use at an assay dependent concentration. To detect mMIP-2 by direct ELISA (using 100µl/well antibody solution) a concentration of at least 0.5µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant mMIP-2.
Neutralising Use at an assay dependent concentration. To yield one-half maximal inhibition [ND50] of the biological activity of mMIP-2 (15 ng/ml), a concentration of 0.52 - 0.9 µg/ml of this antibody is required.

Target

  • FunctionProduced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • C-X-C motif chemokine 2 antibody
    • Chemokine (C X C motif) ligand 2 antibody
    • Chemokine, CXC motif, ligand 2 antibody
    • CINC 2a antibody
    • CINC2a antibody
    • CINC3 antibody
    • CXC chemokine antibody
    • CXCL 2 antibody
    • Cxcl2 antibody
    • CXCL2_HUMAN antibody
    • Cytokine-induced neutrophil chemoattractant 3 antibody
    • GRO 2 antibody
    • GRO b antibody
    • GRO protein, beta antibody
    • Gro-beta antibody
    • GRO-beta(5-73) antibody
    • GRO-beta-T antibody
    • GRO2 antibody
    • GRO2 oncogene antibody
    • GROb antibody
    • GRObeta antibody
    • Growth regulated protein beta antibody
    • Growth-regulated protein beta antibody
    • GROX antibody
    • Hematopoietic synergistic factor antibody
    • HSF antibody
    • Macrophage inflammatory protein 2 alpha antibody
    • Macrophage inflammatory protein 2 antibody
    • Macrophage inflammatory protein 2-alpha antibody
    • Melanoma growth stimulatory activity beta antibody
    • MGSA b antibody
    • MGSA beta antibody
    • MIP 2 antibody
    • MIP 2a antibody
    • MIP2 alpha antibody
    • MIP2 antibody
    • MIP2-alpha antibody
    • MIP2A antibody
    • MIP2alpha antibody
    • SB-251353 antibody
    • SCYB 2 antibody
    • Scyb antibody
    • SCYB2 antibody
    • Small inducible cytokine subfamily B, member 2 antibody
    see all

References for Anti-CXCL2 antibody (ab9950)

This product has been referenced in:
  • Zhang Q  et al. Toll-like receptor 4 contributes to acute kidney injury after cardiopulmonary resuscitation in mice. Mol Med Rep 14:2983-90 (2016). Mouse . Read more (PubMed: 27510583) »
  • Oue E  et al. CXCL2 synthesized by oral squamous cell carcinoma is involved in cancer-associated bone destruction. Biochem Biophys Res Commun 424:456-61 (2012). Neutralising . Read more (PubMed: 22771802) »

See all 2 Publications for this product

Product Wall

Thank you for your enquiry. We have twelve different antibodies raised against CXCL-2-protein (macrophage inflammatory protein). All of the information that we have available for each antibody is listed on the online datasheet. For example, ab9950...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"