Overview

  • Product nameAnti-CXCL7 antibody [5C7]
    See all CXCL7 primary antibodies
  • Description
    Mouse monoclonal [5C7] to CXCL7
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length NAP2 protein (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab40936 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notesELISA: 1/10000. This dilution will yield 1.0 OD using alkaline phosphatase conjugated rabbit anti-mouse Ig. May be used as capture IgG at 1-2µg/ml

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionLA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
    • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
    • Post-translational
      modifications
      Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)).
      Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor.
      NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils.
      NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets.
    • Cellular localizationSecreted.
    • Information by UniProt
    • Database links
    • Alternative names
      • B TG1 antibody
      • Beta TG antibody
      • Beta thromboglobulin antibody
      • Beta-TG antibody
      • C-X-C motif chemokine 7 antibody
      • Chemokine (C X C motif) ligand 7 antibody
      • Connective tissue activating peptide III antibody
      • CTAP 3 antibody
      • CTAP III antibody
      • CTAP-III antibody
      • CTAP-III(1-81) antibody
      • CTAP3 antibody
      • CTAPIII antibody
      • CXC chemokine ligand 7 antibody
      • CXCL 7 antibody
      • CXCL7 antibody
      • CXCL7_HUMAN antibody
      • LA PF 4 antibody
      • LA-PF4 antibody
      • LDGF antibody
      • Leukocyte derived growth factor antibody
      • Leukocyte-derived growth factor antibody
      • Low-affinity platelet factor IV antibody
      • Macrophage-derived growth factor antibody
      • MDGF antibody
      • NAP 2 antibody
      • NAP-2 antibody
      • NAP-2(1-63) antibody
      • NAP-2(1-66) antibody
      • NAP-2(73) antibody
      • NAP-2(74) antibody
      • Neutrophil activating peptide 2 antibody
      • Neutrophil-activating peptide 2(1-63) antibody
      • PBP antibody
      • Platelet basic protein antibody
      • PPBP antibody
      • Pro platelet basic protein (chemokine (C-X-C motif) ligand 7) antibody
      • Pro platelet basic protein antibody
      • SCYB7 antibody
      • Small inducible cytokine subfamily B member 7 antibody
      • Small-inducible cytokine B7 antibody
      • TC1 antibody
      • TC2 antibody
      • TGB antibody
      • TGB1 antibody
      • THBGB antibody
      • THBGB1 antibody
      • Thrombocidin 1 antibody
      • Thrombocidin 2 antibody
      • Thromboglobulin, beta-1 antibody
      see all

    References for Anti-CXCL7 antibody [5C7] (ab40936)

    ab40936 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab40936.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"