Overview

  • Product nameAnti-CXCL7 antibody
    See all CXCL7 primary antibodies
  • Description
    Rabbit polyclonal to CXCL7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-128 of Human NAP2 (NP_002695.1).

  • Positive control
    • Human spleen whole cell lysate; NAP2 transfected 293T whole cell lysate

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab103625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 14 kDa.

Target

  • FunctionLA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    Proteolytic removal of residues 1-9 produces the active peptide connective tissue-activating peptide III (CTAP-III) (low-affinity platelet factor IV (LA-PF4)).
    Proteolytic removal of residues 1-13 produces the active peptide beta-thromboglobulin, which is released from platelets along with platelet factor 4 and platelet-derived growth factor.
    NAP-2(1-66) is produced by proteolytical processing, probably after secretion by leukocytes other than neutrophils.
    NAP-2(73) and NAP-2(74) seem not be produced by proteolytical processing of secreted precursors but are released in an active form from platelets.
  • Cellular localizationSecreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • B TG1 antibody
    • Beta TG antibody
    • Beta thromboglobulin antibody
    • Beta-TG antibody
    • C-X-C motif chemokine 7 antibody
    • Chemokine (C X C motif) ligand 7 antibody
    • Connective tissue activating peptide III antibody
    • CTAP 3 antibody
    • CTAP III antibody
    • CTAP-III antibody
    • CTAP-III(1-81) antibody
    • CTAP3 antibody
    • CTAPIII antibody
    • CXC chemokine ligand 7 antibody
    • CXCL 7 antibody
    • CXCL7 antibody
    • CXCL7_HUMAN antibody
    • LA PF 4 antibody
    • LA-PF4 antibody
    • LDGF antibody
    • Leukocyte derived growth factor antibody
    • Leukocyte-derived growth factor antibody
    • Low-affinity platelet factor IV antibody
    • Macrophage-derived growth factor antibody
    • MDGF antibody
    • NAP 2 antibody
    • NAP-2 antibody
    • NAP-2(1-63) antibody
    • NAP-2(1-66) antibody
    • NAP-2(73) antibody
    • NAP-2(74) antibody
    • Neutrophil activating peptide 2 antibody
    • Neutrophil-activating peptide 2(1-63) antibody
    • PBP antibody
    • Platelet basic protein antibody
    • PPBP antibody
    • Pro platelet basic protein (chemokine (C-X-C motif) ligand 7) antibody
    • Pro platelet basic protein antibody
    • SCYB7 antibody
    • Small inducible cytokine subfamily B member 7 antibody
    • Small-inducible cytokine B7 antibody
    • TC1 antibody
    • TC2 antibody
    • TGB antibody
    • TGB1 antibody
    • THBGB antibody
    • THBGB1 antibody
    • Thrombocidin 1 antibody
    • Thrombocidin 2 antibody
    • Thromboglobulin, beta-1 antibody
    see all

Anti-CXCL7 antibody images

  • Anti-CXCL7 antibody (ab103625) at 1 µg/ml + Human spleen tissue lysate at 50 µg

    Predicted band size : 14 kDa
  • All lanes : Anti-CXCL7 antibody (ab103625) at 1 µg/ml

    Lane 1 : NAP2 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 14 kDa
    Observed band size : 14 kDa

References for Anti-CXCL7 antibody (ab103625)

ab103625 has not yet been referenced specifically in any publications.

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