Anti-CXCR1 antibody [MM0221-7D22] (ab89251)


  • Product nameAnti-CXCR1 antibody [MM0221-7D22]
    See all CXCR1 primary antibodies
  • Description
    Mouse monoclonal [MM0221-7D22] to CXCR1
  • Tested applicationsSuitable for: IHC-Fr, Neutralising, Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human recombinant CXCR1


  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityProtein G purified
  • Purification notesThe IgG fraction of culture supernatant was purified by Protein G affinity chromatography.
  • ClonalityMonoclonal
  • Clone numberMM0221-7D22
  • IsotypeIgG2a
  • Research areas


Our Abpromise guarantee covers the use of ab89251 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/20 - 1/100.
Neutralising Use at an assay dependent concentration.
Flow Cyt 1/50 - 1/200. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.


  • FunctionReceptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C C antibody
    • C C CKR 1 antibody
    • C-X-C chemokine receptor type 1 antibody
    • CCCKR1 antibody
    • CD 181 antibody
    • CD128 antibody
    • CD181 antibody
    • CD181 antigen antibody
    • CDw128a antibody
    • Chemokine (C X C motif) receptor 1 antibody
    • Chemokine (C X C) receptor 1 antibody
    • Chemokine receptor 1 antibody
    • CKR 1 antibody
    • CMKAR1 antibody
    • CXC-R1 antibody
    • CXCR 1 antibody
    • CXCR-1 antibody
    • CXCR1 antibody
    • CXCR1_HUMAN antibody
    • High affinity interleukin 8 receptor A antibody
    • High affinity interleukin-8 receptor A antibody
    • IL 8 receptor type 1 antibody
    • IL 8R A antibody
    • IL-8 receptor type 1 antibody
    • IL-8R A antibody
    • IL8 receptor antibody
    • IL8 receptor type 1 antibody
    • IL8R1 antibody
    • IL8RA antibody
    • IL8RBA antibody
    • Interleukin 8 receptor alpha antibody
    • Interleukin 8 receptor type 1 antibody
    • Interleukin 8 receptor type A antibody
    see all

References for Anti-CXCR1 antibody [MM0221-7D22] (ab89251)

ab89251 has not yet been referenced specifically in any publications.

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Je viens d'avoir la confirmation que les épitopes des deux anti-CXCR1 n'ont malheureusement pas été déterminés.

N'hésitez pas à me contacter de nouveau si vous avez d'autres questions.

Merci de nous avoir contactés.

Veuillez trouver ci-joints les 2 alignements de séquences, un pour le CXCR1, l'autre pour IL8.
Je suis en contact avec les laboratoires afin de savoir si les épitpes de ab10400 et ab89251...

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Thank you for contacting us.

With antibodies these two terms have similar meaning i.e. antibodies inhibit or neutralizes the cellular response either by binding to receptors, ligand or other cell signalling downstream proteins.


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