The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa.
May be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Very high levels in testis and very low levels in brain. Also found in myeloid Leukemia cell lines.
Belongs to the cyclin family. Cyclin AB subfamily.
Expression increases in early G1 phase and reaches highest levels during the S and G2/M phases.
Yang L et al. Transcriptional co-activator with PDZ-binding motif overexpression promotes cell proliferation and transcriptional co-activator with PDZ-binding motif deficiency induces cell cycle arrest in neuroblastoma. Oncol Lett13:4295-4301 (2017).
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