The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 49 kDa).
FunctionMay be involved in the control of the cell cycle at the G1/S (start) and G2/M (mitosis) transitions. May primarily function in the control of the germline meiotic cell cycle and additionally in the control of mitotic cell cycle in some somatic cells.
Tissue specificityVery high levels in testis and very low levels in brain. Also found in myeloid Leukemia cell lines.
Sequence similaritiesBelongs to the cyclin family. Cyclin AB subfamily.
Developmental stageExpression increases in early G1 phase and reaches highest levels during the S and G2/M phases.