Overview

  • Product name
  • Description
    Rabbit polyclonal to Cyclin
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment containing a sequence corresponding to a region within amino acids 1-377 of Human Cyclin.

  • Positive control
    • HCT116 whole cell lysate, Human RF48 xenograft tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab152116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 43 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Relevance
    The cell cycle is regulated by the interplay of many molecules. Key among these are the cyclins which are expressed and then degraded in a concerted fashion to drive the stages of the cell cycle. Cyclins combine with cyclin dependent kinases (cdks) to form activated kinases that phosphorylate targets leading to cell cycle regulation. A breakdown in the regulation of this cycle can lead to out of control growth and contribute to tumor formation. Defects in many of the molecules that regulate the cell cycle have been implicated in cancer
  • Database links
  • Alternative names
    • CCNI antibody
    • CYC1 antibody
    • Cyclin 1 antibody
    • Cyclin I antibody
    • Cyclin ITI antibody
    • CYI antibody
    see all

Images

  • Anti-Cyclin antibody (ab152116) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg

    Predicted band size : 43 kDa
  • Immunohistochemical analysis of paraffin-embedded Human RF48 xenograft tissue labeling Cyclin using ab152116 at a 1/500 dilution.

References

ab152116 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab152116.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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