Overview

  • Product name
  • Description
    Rabbit polyclonal to Cyclin
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The immunogen sequence is 228 and 414 of cyclin I(Uniprot:Q14094)

  • Positive control
    • K562, Jurkat and Raji whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab153877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 43 kDa.

Target

  • Relevance
    The cell cycle is regulated by the interplay of many molecules. Key among these are the cyclins which are expressed and then degraded in a concerted fashion to drive the stages of the cell cycle. Cyclins combine with cyclin dependent kinases (cdks) to form activated kinases that phosphorylate targets leading to cell cycle regulation. A breakdown in the regulation of this cycle can lead to out of control growth and contribute to tumor formation. Defects in many of the molecules that regulate the cell cycle have been implicated in cancer
  • Database links
  • Alternative names
    • CCNI antibody
    • CYC1 antibody
    • Cyclin 1 antibody
    • Cyclin I antibody
    • Cyclin ITI antibody
    • CYI antibody
    see all

Images

  • All lanes : Anti-Cyclin antibody (ab153877) at 1/1000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Raji whole cell lysate
    Lane 3 : K562 whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 43 kDa



    10% SDS PAGE

References

ab153877 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab153877.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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