Anti-Cyclin B1 antibody (ab7957)
- Product nameAnti-Cyclin B1 antibodySee all Cyclin B1 primary antibodies ...
- DescriptionRabbit polyclonal to Cyclin B1
- SpecificityReacts with cyclin B1
- Tested applicationsIHC-Fr, IP, WB more details
- Species reactivityReacts with: Human
Synthetic peptide: TLPQLNSALVQDLAKAVAKV, corresponding to C terminal amino acids 414-433 of Human Cyclin B1.
- Positive controlHeLa and K-562
- Storage instructionsStore at +4°C. Do not freeze.
- Storage bufferPBS with 0.1% sodium azide
- Concentration information loading...
- PurityIgG fraction
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab7957 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||IHC-Fr: Use at an assay dependent dilution.|
|IP||IP: Use at an assay dependent dilution.|
|WB||WB: Use at an assay dependent dilution. Detects a band of approximately 58 kDa (predicted molecular weight: 49 kDa).Can be blocked with Cyclin B1 (C-term) peptide (human) (ab8012).|
- FunctionEssential for the control of the cell cycle at the G2/M (mitosis) transition.
- Sequence similaritiesBelongs to the cyclin family. Cyclin AB subfamily.
- Developmental stageAccumulates steadily during G2 and is abruptly destroyed at mitosis.
modificationsUbiquitinated by the SCF(NIPA) complex during interphase, leading to its destruction. Not ubiquitinated during G2/M phases.
- Cellular localizationCytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.
- CCNB 1 antibodyCCNB antibodyCCNB1 antibody
- CCNB1_HUMAN antibodyG2 mitotic specific cyclin B1 antibodyG2/mitotic-specific cyclin-B1 antibody
Anti-Cyclin B1 antibody images
Predicted band size : 49 kDa
ab7957 staining Cyclin B1 in HeLa whole cell lysate
References for Anti-Cyclin B1 antibody (ab7957)
This product has been referenced in:
- van der Horst A & Khanna KK The peptidyl-prolyl isomerase Pin1 regulates cytokinesis through Cep55. Cancer Res 69:6651-9 (2009). WB ; Human . Read more (PubMed: 19638580) »
- Sasaki T et al. Phosphorylation regulates SIRT1 function. PLoS ONE 3:e4020 (2008). WB ; Human . Read more (PubMed: 19107194) »