Anti-Cyclin D1 antibody [EPR2241] (ab134175)

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ab134175 has been referenced in 60 publications.

  • Wu VC  et al. The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes. Sci Rep 7:39121 (2017). WB ; Human . PubMed: 28102204
  • Lu T  et al. Adamts18 deficiency promotes colon carcinogenesis by enhancing ß-catenin and p38MAPK/ERK1/2 signaling in the mouse model of AOM/DSS-induced colitis-associated colorectal cancer. Oncotarget 8:18979-18990 (2017). IHC ; Mouse . PubMed: 28145888
  • Zhang C  et al. Growth of tyrosine kinase inhibitor-resistant Philadelphia-positive acute lymphoblastic leukemia: Role of bone marrow stromal cells. Oncol Lett 13:2059-2070 (2017). WB . PubMed: 28454362
  • Tian L  et al. Siamese crocodile bile induces apoptosis in NCI-H1299 human non-small cell lung cancer cells via a mitochondria-mediated intrinsic pathway and inhibits tumorigenesis. Mol Med Rep 15:1727-1737 (2017). PubMed: 28259903
  • Yan L  et al. Downregulation of microRNA-30d promotes cell proliferation and invasion by targeting LRH-1 in colorectal carcinoma. Int J Mol Med 39:1371-1380 (2017). WB ; Human . PubMed: 28440426
  • Wang T  et al. Fibulin-4 is associated with prognosis of endometrial cancer patients and inhibits cancer cell invasion and metastasis via Wnt/ß-catenin signaling pathway. Oncotarget 8:18991-19012 (2017). WB ; Human . PubMed: 28177909
  • Yan KS  et al. Non-equivalence of Wnt and R-spondin ligands during Lgr5(+) intestinal stem-cell self-renewal. Nature 545:238-242 (2017). IHC-P ; Mouse . PubMed: 28467820
  • Ding L  et al. MicroRNA-27a contributes to the malignant behavior of gastric cancer cells by directly targeting PH domain and leucine-rich repeat protein phosphatase 2. J Exp Clin Cancer Res 36:45 (2017). WB ; Human . PubMed: 28327189
  • Hong Y  et al. miR-96 promotes cell proliferation, migration and invasion by targeting PTPN9 in breast cancer. Sci Rep 6:37421 (2016). WB ; Human . PubMed: 27857177
  • Zhang X  et al. MicroRNA-195 suppresses colorectal cancer cells proliferation via targeting FGF2 and regulating Wnt/ß-catenin pathway. Am J Cancer Res 6:2631-2640 (2016). WB ; Human . PubMed: 27904776
  • Liang L  et al. Babao Dan attenuates hepatic fibrosis by inhibiting hepatic stellate cells activation and proliferation via TLR4 signaling pathway. Oncotarget 7:82554-82566 (2016). WB ; Rat . PubMed: 27776340
  • Li YI  et al. Increased autophagic response in a population of metastatic breast cancer cells. Oncol Lett 12:523-529 (2016). ICC/IF ; Human . PubMed: 27347175
  • Qu F  et al. MicroRNA-26a induces osteosarcoma cell growth and metastasis via the Wnt/ß-catenin pathway. Oncol Lett 11:1592-1596 (2016). WB ; Human . PubMed: 26893786
  • Misiewicz-Krzeminska I  et al. Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma. Clin Cancer Res 22:207-17 (2016). PubMed: 26341922
  • Asher M  et al. Ataxin-1 regulates proliferation of hippocampal neural precursors. Neuroscience N/A:N/A (2016). PubMed: 26876606
  • Jin Y & Dai Z USO1 promotes tumor progression via activating Erk pathway in multiple myeloma cells. Biomed Pharmacother 78:264-71 (2016). WB ; Human . PubMed: 26898451
  • Xing Y  et al. Silencing of ILK attenuates the abnormal proliferation and migration of human Tenon's capsule fibroblasts induced by TGF-ß2. Int J Mol Med N/A:N/A (2016). WB ; Human . PubMed: 27315599
  • Zhang QS  et al. Downregulation of SENP1 inhibits cell proliferation, migration and promotes apoptosis in human glioma cells. Oncol Lett 12:217-221 (2016). WB ; Human . PubMed: 27347128
  • Li J  et al. ATF3 suppresses ESCC via downregulation of ID1. Oncol Lett 12:1642-1648 (2016). IHC-P ; Human . PubMed: 27602100
  • Gao K  et al. Deregulated WWOX is involved in a negative feedback loop with microRNA-214-3p in osteosarcoma. Int J Mol Med N/A:N/A (2016). WB . PubMed: 27840941
  • Lujic N  et al. Recurrence of giant cell tumour of bone: role of p53, cyclin D1, ß-catenin and Ki67. Int Orthop 40:2393-2399 (2016). PubMed: 27658412
  • Park E  et al. Inhibitory Effect of Yongdamsagan-Tang Water Extract, a Traditional Herbal Formula, on Testosterone-Induced Benign Prostatic Hyperplasia in Rats. Evid Based Complement Alternat Med 2016:1428923 (2016). WB ; Rat . PubMed: 27504137
  • Yuan S  et al. Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-?B pathway. Cell Cycle 15:2895-2905 (2016). PubMed: 27436181
  • Xia X  et al. Inhibitor of DNA binding 1 regulates cell cycle progression of endothelial progenitor cells through induction of Wnt2 expression. Mol Med Rep N/A:N/A (2016). WB ; Mouse . PubMed: 27432753
  • Mao M & Wang W SerpinE2 promotes multiple cell proliferation and drug resistance in osteosarcoma. Mol Med Rep 14:881-7 (2016). PubMed: 27221371
  • Wu J  et al. Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity. Cell Death Dis 7:e2339 (2016). WB . PubMed: 27537522
  • Ye GF  et al. Secreted Protein Acidic and Rich in Cysteine Modulates Molecular Arterial Homeostasis of Human Arterial Smooth Muscle Cells In Vitro. J Mol Neurosci 60:509-516 (2016). WB ; Human . PubMed: 27561928
  • Zhao X  et al. Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms. Mol Med Rep 14:1067-74 (2016). WB ; Human . PubMed: 27279418
  • Xia W  et al. Circular RNA has_circ_0067934 is upregulated in esophageal squamous cell carcinoma and promoted proliferation. Sci Rep 6:35576 (2016). WB ; Human . PubMed: 27752108
  • Xu J  et al. miR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6. Sci Rep 6:28968 (2016). PubMed: 27364926
  • Majaz S  et al. Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression. Cell Biosci 6:47 (2016). PubMed: 27486509
  • He B  et al. Upregulated microRNA-143 inhibits cell proliferation in human nasopharyngeal carcinoma. Oncol Lett 12:5023-5028 (2016). WB ; Human . PubMed: 28105209
  • Han A  et al. p63a modulates c-Myc activity via direct interaction and regulation of MM1 protein stability. Oncotarget 7:44277-44287 (2016). WB ; Human . PubMed: 27341130
  • Tan BL  et al. Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/ß-catenin downstream signaling pathway in brewers' rice-treated rats with azoxymethane-induced colon carcinogenesis. BMC Complement Altern Med 15:205 (2015). WB ; Rat . PubMed: 26122204
  • Markiewicz E  et al. Nonlinear ionizing radiation-induced changes in eye lens cell proliferation, cyclin D1 expression and lens shape. Open Biol 5:150011 (2015). PubMed: 25924630
  • Pozo K  et al. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget 6:12080-93 (2015). WB . PubMed: 25900242
  • Ralhan R  et al. Immunohistochemical Subcellular Localization of Protein Biomarkers Distinguishes Benign from Malignant Thyroid Nodules: Potential for Fine-Needle Aspiration Biopsy Clinical Application. Thyroid 25:1224-34 (2015). IHC . PubMed: 26131603
  • Wang X  et al. Synergistic control of sex hormones by 17ß-HSD type 7: a novel target for estrogen-dependent breast cancer. J Mol Cell Biol 7:568-79 (2015). PubMed: 25966904
  • Zhang P  et al. Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-a protein turnover. Cell Death Dis 6:e1687 (2015). PubMed: 25766326
  • Ye GD  et al. OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and is Downregulated in Human Colorectal Tumors. Gastroenterology N/A:N/A (2015). PubMed: 26619963
  • Bai M  et al. OCT4 pseudogene 5 upregulates OCT4 expression to promote proliferation by competing with miR-145 in endometrial carcinoma. Oncol Rep 33:1745-52 (2015). PubMed: 25634023
  • Xu Z  et al. Quantitative Proteomics Reveals That the Inhibition of Na(+)/K(+)-ATPase Activity Affects S-Phase Progression Leading to a Chromosome Segregation Disorder by Attenuating the Aurora A Function in Hepatocellular Carcinoma Cells. J Proteome Res 14:4594-602 (2015). PubMed: 26491887
  • Gao K  et al. Tumor suppressor SPOP mediates the proteasomal degradation of progesterone receptors (PRs) in breast cancer cells. Am J Cancer Res 5:3210-20 (2015). Human . PubMed: 26693071
  • Gao K  et al. HDGF-related protein-2 (HRP-2) acts as an oncogene to promote cell growth in hepatocellular carcinoma. Biochem Biophys Res Commun 458:849-55 (2015). WB ; Human . PubMed: 25689719
  • Shi J  et al. Regulation of ß-catenin transcription activity by leupaxin in hepatocellular carcinoma. Tumour Biol N/A:N/A (2015). PubMed: 26361959
  • Lan Z  et al. Amantadine inhibits cellular proliferation and induces the apoptosis of hepatocellular cancer cells in vitro. Int J Mol Med 36:904-10 (2015). PubMed: 26201988
  • Cai JQ  et al. Upregulation of HOXB7 promotes the tumorigenesis and progression of gastric cancer and correlates with clinical characteristics. Tumour Biol N/A:N/A (2015). PubMed: 26307396
  • Ren W  et al. FHL1 inhibits the growth of tongue squamous cell carcinoma cells via G1/S cell cycle arrest. Mol Med Rep 12:3958-64 (2015). PubMed: 26017856
  • Liu Y  et al. Gpr177-mediated Wnt Signaling Is Required for Secondary Palate Development. J Dent Res 94:961-7 (2015). PubMed: 25922332
  • Lee JW  et al. A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress. PLoS One 10:e0122628 (2015). PubMed: 25897662
  • Mirzaa GM  et al. De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome. Nat Genet 46:510-5 (2014). WB ; Human . PubMed: 24705253
  • Wei C  et al. Elevated expression of TANK-binding kinase 1 enhances tamoxifen resistance in breast cancer. Proc Natl Acad Sci U S A 111:E601-10 (2014). PubMed: 24449872
  • Brodowska K  et al. Effects of metformin on retinoblastoma growth in vitro and in vivo. Int J Oncol 45:2311-24 (2014). PubMed: 25215935
  • Ito K  et al. Overexpression of Cdk6 and Ccnd1 in chondrocytes inhibited chondrocyte maturation and caused p53-dependent apoptosis without enhancing proliferation. Oncogene N/A:N/A (2013). Mouse . PubMed: 23624920
  • Zhong LP  et al. Elevated cyclin D1 expression is predictive for a benefit from TPF induction chemotherapy in oral squamous cell carcinoma patients with advanced nodal disease. Mol Cancer Ther 12:1112-21 (2013). IHC ; Human . PubMed: 23515614
  • Guo SL  et al. Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency. Nat Commun 4:2544 (2013). WB, IHC-P ; Human . PubMed: 24149576
  • Hua Y  et al. Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma. Clin Cancer Res 19:6242-51 (2013). Mouse . PubMed: 24077352
  • Sreevalsan S & Safe S The cannabinoid WIN 55,212-2 decreases specificity protein transcription factors and the oncogenic cap protein eIF4E in colon cancer cells. Mol Cancer Ther 12:2483-93 (2013). PubMed: 24030632
  • Fu WY  et al. Suppression of liver regeneration affects hepatic graft survival in small-for-size liver transplantation in rats. Hepatol Res : (2012). PubMed: 22882432
  • Feng Z  et al. CCND1 as a predictive biomarker of neoadjuvant chemotherapy in patients with locally advanced head and neck squamous cell carcinoma. PLoS One 6:e26399 (2011). IHC-P ; Human . PubMed: 22065993


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