Anti-Cyclin E1 antibody [0.T.206] (ab33176)

Overview

  • Product nameAnti-Cyclin E1 antibody [0.T.206]
    See all Cyclin E1 primary antibodies
  • Description
    Mouse monoclonal [0.T.206] to Cyclin E1
  • Specificityab33176 recognises p52 cyclin E1.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Recombinant full length protein corresponding to Human Cyclin E1.

Properties

Applications

Our Abpromise guarantee covers the use of ab33176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • FunctionEssential for the control of the cell cycle at the G1/S (start) transition.
  • Tissue specificityHighly expressed in testis and placenta. Low levels in bronchial epithelial cells.
  • Sequence similaritiesBelongs to the cyclin family. Cyclin E subfamily.
  • Post-translational
    modifications
    Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • CCNE antibody
    • Ccne1 antibody
    • CCNE1_HUMAN antibody
    • cyclin E variant ex5del antibody
    • cyclin E variant ex7del antibody
    • Cyclin E1 antibody
    • Cyclin Es antibody
    • Cyclin Et antibody
    • CyclinE antibody
    • G1/S specific cyclin E antibody
    • G1/S-specific cyclin-E1 antibody
    see all

References for Anti-Cyclin E1 antibody [0.T.206] (ab33176)

ab33176 has not yet been referenced specifically in any publications.

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