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Rabbit polyclonal to Cyclin E1, prediluted
HumanPredicted to work with:
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive).
- SKBR3 cells, MAD109 cells, breast carcinoma and placenta.
Shipped at 4°C. Store at +4°C. Do Not Freeze.
Preservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6
Concentration information loading...
Immunogen affinity purified
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Ready to use for 10 min at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Essential for the control of the cell cycle at the G1/S (start) transition.
Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
Belongs to the cyclin family. Cyclin E subfamily.
Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
- CCNE antibody
- Ccne1 antibody
- CCNE1_HUMAN antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cyclin E1 antibody, prediluted (ab15197)
ab15197 staining Cyclin E in breast carcinoma by Immunohistochemistry (FFPE-sections).
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"