Overview

  • Product nameAnti-Cyclin G antibody [11C8]
    See all Cyclin G primary antibodies
  • Description
    Mouse monoclonal [11C8] to Cyclin G
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment:Prokaryotic recombinant protein corresponding to 142 amino acids of the C terminal region of (human) cyclin G1.

  • Positive control
    • Immunohistochemistry: Tonsil. Western Blotting: MCF7 cell line.

Properties

Applications

Our Abpromise guarantee covers the use of ab49274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
  • Application notesIHC-P: 1/20 - 1/40. High temperature antigen unmasking technique. 60 minutes primary antibody incubation at 25oC and standard ABC technique are recommended.
    WB: 1/100 - 1/250. Predicted molecular weight: 34 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
    • Tissue specificityHigh levels in skeletal muscle, ovary, kidney and colon.
    • Sequence similaritiesBelongs to the cyclin family. Cyclin G subfamily.
    • Developmental stageVery low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells consistent high levels are found throughout the cell cycle.
    • Cellular localizationNucleus. DNA replication foci after DNA damage.
    • Information by UniProt
    • Database links
    • Alternative names
      • CCNG 1 antibody
      • CCNG antibody
      • CCNG1 antibody
      • CCNG1_HUMAN antibody
      • CYCG1 antibody
      • Cyclin G antibody
      • Cyclin G1 antibody
      • Cyclin-G antibody
      • Cyclin-G1 antibody
      see all

    References for Anti-Cyclin G antibody [11C8] (ab49274)

    ab49274 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab49274.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"