Anti-Cyclin H antibody [EPR3928] (ab111933)

Overview

  • Product nameAnti-Cyclin H antibody [EPR3928]
    See all Cyclin H primary antibodies
  • Description
    Rabbit monoclonal [EPR3928] to Cyclin H
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to residues from Human Cyclin H.

  • Positive control
    • Jurkat, A431, K562 and HeLa cell lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab111933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 38 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • FunctionRegulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
    • Sequence similaritiesBelongs to the cyclin family. Cyclin C subfamily.
    • Cellular localizationNucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • 6330408H09Rik antibody
      • AI661354 antibody
      • AV102684 antibody
      • AW538719 antibody
      • CAK antibody
      • CAK complex subunit antibody
      • ccnh antibody
      • CCNH_HUMAN antibody
      • CDK activating kinase antibody
      • CDK activating kinase complex subunit antibody
      • Cyclin dependent kinase activating kinase antibody
      • cyclin dependent kinase activating kinase complex subunit antibody
      • Cyclin H antibody
      • Cyclin-H antibody
      • CyclinH antibody
      • MO15 associated protein antibody
      • MO15-associated protein antibody
      • p34 antibody
      • p36 antibody
      • p37 antibody
      see all

    Anti-Cyclin H antibody [EPR3928] images

    • All lanes : Anti-Cyclin H antibody [EPR3928] (ab111933) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : A431 cell lsyate
      Lane 3 : K562 cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 38 kDa

    References for Anti-Cyclin H antibody [EPR3928] (ab111933)

    ab111933 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"