Overview

  • Product name
    Anti-Cyclophilin B antibody
    See all Cyclophilin B primary antibodies
  • Description
    Rabbit polyclonal to Cyclophilin B
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Dog, Human
    Predicted to work with: Chicken, Cow
  • Immunogen

    Synthetic peptide corresponding to Human Cyclophilin B aa 194-208.
    Sequence:

    CGKIEVEKPFAIAKE


    Database link: P23284

  • Positive control
    • Rat liver lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab171122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent concentration.
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 24 kDa.

Target

  • Function
    PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • Involvement in disease
    Defects in PPIB are the cause of osteogenesis imperfecta type 9 (OI9) [MIM:259440]. OI9 is a connective tissue disorder characterized by bone fragility, low bone mass and bowing of limbs due to multiple fractures. Short limb dwarfism and blue sclerae are observed in some but not all patients.
  • Sequence similarities
    Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
    Contains 1 PPIase cyclophilin-type domain.
  • Cellular localization
    Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • Database links
  • Alternative names
    • AA408962 antibody
    • AA553318 antibody
    • AI844835 antibody
    • Cphn 2 antibody
    • Cphn2 antibody
    • Cyclophilin B antibody
    • Cyclophilin like protein antibody
    • CyP 20b antibody
    • CYP S1 antibody
    • CYP-S1 antibody
    • CYPB antibody
    • EC 5.2.1.8 antibody
    • MGC14109 antibody
    • MGC2224 antibody
    • OI9 antibody
    • peptidyl prolyl cis trans isomerase B antibody
    • Peptidyl prolyl cis trans isomerase B precursor antibody
    • Peptidyl-prolyl cis-trans isomerase B antibody
    • peptidylprolyl isomerase B (cyclophilin B) antibody
    • Peptidylprolyl isomerase B antibody
    • PPIase antibody
    • PPIase B antibody
    • Ppib antibody
    • PPIB_HUMAN antibody
    • Rotamase antibody
    • Rotamase B antibody
    • S cyclophilin antibody
    • S-cyclophilin antibody
    • SCYLP antibody
    see all

Images

  • Lanes 1 & 3 : Anti-Cyclophilin B antibody (ab171122) at 1/2000 dilution
    Lane 2 : Anti-Cyclophilin B antibody (ab171122) at 1/1000 dilution
    Lane 4 : Anti-Cyclophilin B antibody (ab171122) at 1/4000 dilution

    Lane 1 : rat liver lysate
    Lane 2 : rat liver lysate
    Lane 3 : rat liver lysate
    Lane 4 : rat liver lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 24 kDa

References

ab171122 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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