Overview

  • Product name
    Cyclothiazide
  • Description
    AMPA receptor desensitisation inhibitor
  • Biological description
    Positive allosteric modulator of AMPA receptors. Produces a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current. Also available in Kit: Ionotropic agonists (ab120323).
  • Purity
    > 98%

Properties

Associated products

References

This product has been referenced in:
  • Fucile S  et al. Effects of cyclothiazide on GluR1/AMPA receptors. Proc Natl Acad Sci U S A 103:2943-7 (2006). Read more (PubMed: 16473938) »
  • Desai MA  et al. Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists. J Pharmacol Exp Ther 272:38-43 (1995). Read more (PubMed: 7529311) »
  • Partin KM  et al. Cyclothiazide differentially modulates desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor splice variants. Mol Pharmacol 46:129-38 (1994). Read more (PubMed: 8058047) »

See all 14 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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