Overview

  • Product nameCyclothiazide
  • Description
    AMPA receptor desensitisation inhibitor
  • Biological descriptionPositive allosteric modulator of AMPA receptors. Produces a fast inhibition of AMPA receptor desensitization and a much slower potentiation of the AMPA current. Also available in Kit: Ionotropic agonists (ab120323).
  • Purity> 98%

Properties

    Associated products

    References for Cyclothiazide (ab120061)

    This product has been referenced in:
    • Fucile S  et al. Effects of cyclothiazide on GluR1/AMPA receptors. Proc Natl Acad Sci U S A 103:2943-7 (2006). Read more (PubMed: 16473938) »
    • Desai MA  et al. Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists. J Pharmacol Exp Ther 272:38-43 (1995). Read more (PubMed: 7529311) »
    • Partin KM  et al. Cyclothiazide differentially modulates desensitization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor splice variants. Mol Pharmacol 46:129-38 (1994). Read more (PubMed: 8058047) »

    See all 13 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120061.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"