Overview

  • Product name
  • Description
    Rabbit polyclonal to CYP21A2
  • Host species
    Rabbit
  • Specificity
    ab189420 detects endogenous levels of total CYP21A2 protein.
  • Tested applications
    Suitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Positive control
    • Human liver tissue: 293 cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab189420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/20000.
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.
IHC-P Use a concentration of 20 µg/ml.

Target

  • Function
    Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
  • Involvement in disease
    Adrenal hyperplasia 3
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Domain
    The leucine-rich hydrophobic amino acid N-terminal region probably helps to anchor the protein to the microsomal membrane.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CYP21 antibody
    • 21 OHase antibody
    • 21-OHase antibody
    • CA21H antibody
    • CAH1 antibody
    • CP21A_HUMAN antibody
    • CPS1 antibody
    • CYP21A 2 antibody
    • CYP21A2 antibody
    • CYP21B antibody
    • Cytochrome P-450c21 antibody
    • Cytochrome P450 21 antibody
    • Cytochrome P450 C21B antibody
    • Cytochrome P450 XXI antibody
    • Cytochrome P450, family 21, subfamily A, polypeptide 2 antibody
    • Cytochrome P450, subfamily XXIA (steroid 21 hydroxylase, congenital adrenal hyperplasia), polypeptide 2 antibody
    • Cytochrome P450-C21 antibody
    • Cytochrome P450-C21B antibody
    • P450 C21 antibody
    • P450 C21B antibody
    • P450c21B antibody
    • Steroid 21 hydroxylase antibody
    • Steroid 21 monooxygenase antibody
    • Steroid 21-hydroxylase antibody
    see all

Images

  • All lanes : Anti-CYP21A2 antibody (ab189420) at 1/500 dilution

    Lane 1 : 293 cell extracts
    Lane 2 : 293 cell extracts with synthesized peptide

    Predicted band size: 56 kDa

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human liver tissue labeling CYP21A2 with ab189420 at 20 µg/ml.

References

ab189420 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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