The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Use at an assay dependent concentration.
FunctionPlays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Tissue specificityHighest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.
Sequence similaritiesBelongs to the cytochrome P450 family.
ab118446, at 10 µg/ml, staining CYP26A1 in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
References for Anti-CYP26A1 antibody [F27 P6 A1] (ab118446)
has not yet been referenced specifically in any publications.
Publishing research using ab118446? Please let us know so that we can cite the reference in this datasheet.
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