Anti-CYP26A1 antibody [F27 P6 A1] (ab118446)

Overview

  • Product nameAnti-CYP26A1 antibody [F27 P6 A1]
    See all CYP26A1 primary antibodies
  • Description
    Mouse monoclonal [F27 P6 A1] to CYP26A1
  • Tested applicationsSuitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the C terminal of Human CYP26A1 (NP_000774.2).

  • Positive control
    • Human placenta tissue.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab118446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 56 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ELISA Use at an assay dependent concentration.

Target

  • FunctionPlays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
  • Tissue specificityHighest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.
  • Sequence similaritiesBelongs to the cytochrome P450 family.
  • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CP26 antibody
    • CP26A_HUMAN antibody
    • CYP26 antibody
    • CYP26A 1 antibody
    • cyp26a1 antibody
    • Cytochrome P450 26A1 antibody
    • Cytochrome P450 family 26 subfamily A polypeptide 1 antibody
    • Cytochrome P450 retinoic acid-inactivating 1 antibody
    • cytochrome P450, family 26, subfamily A, polypeptide 1 antibody
    • cytochrome P450, subfamily XXVIA, polypeptide 1 antibody
    • Cytochrome P450RAI antibody
    • hP450RAI antibody
    • OTTHUMP00000020102 antibody
    • OTTHUMP00000020103 antibody
    • P450 antibody
    • P450 retinoic acid inactivating 1 antibody
    • P450RAI antibody
    • P450RAI1 antibody
    • Retinoic acid 4 hydroxylase antibody
    • Retinoic acid 4-hydroxylase antibody
    • Retinoic acid metabolizing cytochrome antibody
    • Retinoic acid-metabolizing cytochrome antibody
    see all

Anti-CYP26A1 antibody [F27 P6 A1] images

  • ab118446, at 10 µg/ml, staining CYP26A1 in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-CYP26A1 antibody [F27 P6 A1] (ab118446)

ab118446 has not yet been referenced specifically in any publications.

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