Anti-CYP2C8 antibody (ab103547)
Key features and details
- Rabbit polyclonal to CYP2C8
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-CYP2C8 antibody
See all CYP2C8 primary antibodies -
Description
Rabbit polyclonal to CYP2C8 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein, corresponding to amino acids 1-490 of Human CYP2C8 (AAH20596.1).
-
Positive control
- Human liver tissue lysate, 293T cell line transfected with CYP2C8
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab103547 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 56 kDa.
|
Notes |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 56 kDa. |
Target
-
Function
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol). -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
-
Database links
- Entrez Gene: 1558 Human
- Omim: 601129 Human
- SwissProt: P10632 Human
- Unigene: 709188 Human
-
Alternative names
- CP2C8_HUMAN antibody
- CPC8 antibody
- CYP2C8 antibody
see all
Images
-
Anti-CYP2C8 antibody (ab103547) at 1/500 dilution + Human liver tissue lysate at 50 µg
Predicted band size: 56 kDa -
All lanes : Anti-CYP2C8 antibody (ab103547) at 1/500 dilution
Lane 1 : CYP2C8 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 56 kDa
Datasheets and documents
-
Datasheet download
References (0)
ab103547 has not yet been referenced specifically in any publications.