Overview

  • Product nameAnti-CYP2C8 antibody
    See all CYP2C8 primary antibodies
  • Description
    Rabbit polyclonal to CYP2C8
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-490 of Human CYP2C8 (AAH20596.1).

  • Positive control
    • Human liver tissue lysate, 293T cell line transfected with CYP2C8

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab103547 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.

Target

  • FunctionCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).
  • Sequence similaritiesBelongs to the cytochrome P450 family.
  • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CP2C8_HUMAN antibody
    • CPC8 antibody
    • CYP2C8 antibody
    • CYPIIC8 antibody
    • Cytochrome P450 2C8 antibody
    • Cytochrome P450 family 2 subfamily C polypeptide 8 antibody
    • Cytochrome P450 form 1 antibody
    • Cytochrome P450 IIC2 antibody
    • Cytochrome P450 MP-12 antibody
    • Cytochrome P450 MP-20 antibody
    • Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 8 antibody
    • Flavoprotein linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • MP 12/MP 20 antibody
    • P450 form 1 antibody
    • P450 IIC2 antibody
    • P450 MP 12/MP 20 antibody
    • S mephenytoin 4 hydroxylase antibody
    • S-mephenytoin 4-hydroxylase antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-CYP2C8 antibody images

  • Anti-CYP2C8 antibody (ab103547) at 1/500 dilution + Human liver tissue lysate at 50 µg

    Predicted band size : 56 kDa
  • All lanes : Anti-CYP2C8 antibody (ab103547) at 1/500 dilution

    Lane 1 : CYP2C8 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 56 kDa

References for Anti-CYP2C8 antibody (ab103547)

ab103547 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"