Overview

  • Product name
  • Description
    Rabbit polyclonal to CYP4B1
  • Specificity
    Detects endogenous levels of total CYP4B1 protein
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthesized peptide derived from an internal sequence of human CYP4B1.

  • Positive control
    • Extracts from COLO cells; human lung carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab110012 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 58 kDa.
IHC-P 1/50 - 1/100.

Target

  • Function
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • Tissue specificity
    Detected in the liver and lung (at protein level).
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CP4B1_HUMAN antibody
    • CYP4B1 antibody
    • CYPIVB1 antibody
    • Cytochrome P450 4B1 antibody
    • Cytochrome P450 family 4 subfamily B polypeptide 1 antibody
    • Cytochrome P450 subfamily IVB polypeptide 1 antibody
    • Cytochrome P450-HP antibody
    • Microsomal monooxygenase antibody
    • P450HP antibody
    see all

Images

  • Immunohistochemistry analysis of paraffin embedded human lung carcinoma tissue, using ab110012 at 1/50. The picture on the right is treated with the synthesized peptide.
  • All lanes : Anti-CYP4B1 antibody (ab110012) at 1/500 dilution

    Lane 1 : extracts from COLO cells (5-30 ug total protein) with no immunizing peptide
    Lane 2 : extracts from COLO cells (5-30 ug total protein) with immunizing peptide (5-10 ug)


    Predicted band size : 58 kDa

References

ab110012 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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