Overview

  • Product name
  • Description
    Rabbit polyclonal to CYP8B1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human CYP8B1.
    Database link: Q9UNU6

  • Positive control
    • HEK293T, RAW 264.7 and H9C2 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab191910 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 58 kDa.

Target

  • Function
    Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.
  • Tissue specificity
    Liver.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase antibody
    • 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase antibody
    • CP8B antibody
    • CP8B1_HUMAN antibody
    • CYP12 antibody
    • CYP8B1 antibody
    • CYPVIIIB1 antibody
    • Cytochrome P450 8B1 antibody
    • Cytochrome P450 subfamily VIIIB (sterol 12 alpha hydroxylase) polypeptide 1 antibody
    • Cytochrome P450, family 8, subfamily B, polypeptide 1 antibody
    • Sterol 12-alpha-hydroxylase antibody
    see all

Images

  • All lanes : Anti-CYP8B1 antibody (ab191910)

    Lane 1 : HEK293T whole cell lysate
    Lane 2 : RAW 264.7 whole cell lysate
    Lane 3 : H9C2 whole cell lysate

    Predicted band size: 58 kDa

References

ab191910 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191910.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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