The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 60 kDa).
Use a concentration of 1 - 5 µg/ml.
Use at an assay dependent concentration.
RelevanceCYPIVF11 is a member of the cytochrome P450 family of cytochrome monooxidases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP4F11 has catalytic properties towards endogenous eicosanoids as well as some clinically relevant drugs, and is able to metabolize large molecules such as erythromycin.
Cellular localizationEndoplasmic reticulum membrane; Single pass membrane protein