Overview

  • Product name
  • Description
    Rabbit polyclonal to CysLT1
  • Tested applications
    Suitable for: IHC-P, WB, ICC, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide: YVPRKKASLPEKGEEICKV conjugated to KLH, corresponding to C terminal amino acids 318-337 of Human CysLT1

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.40
    Constituent: Tris buffered saline
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95492 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 39 kDa.
ICC Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.
  • Tissue specificity
    Widely expressed, with highest levels in spleen and peripheral blood leukocytes. Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CLTR1_HUMAN antibody
    • CYSLT 1 antibody
    • CysLT(1) antibody
    • CYSLT1R antibody
    • CYSLTR 1 antibody
    • CYSLTR antibody
    • CysLTR vide supra antibody
    • CysLTR1 antibody
    • Cysteinyl leukotriene D4 receptor antibody
    • Cysteinyl leukotriene receptor 1 antibody
    • G-protein coupled receptor HG55 antibody
    • HG55 antibody
    • HMTMF81 antibody
    • LTD4 receptor antibody
    • MGC46139 antibody
    see all

References

This product has been referenced in:
  • Na JY  et al. Pretreatment of 6-shogaol attenuates oxidative stress and inflammation in middle cerebral artery occlusion-induced mice. Eur J Pharmacol 788:241-7 (2016). WB . Read more (PubMed: 27346834) »

See 1 Publication for this product

Customer reviews and Q&As

Thank you for contacting us and for pointing out the error on the datasheet.

The antibody is presented in TBS, pH 7.4, 300ug in 500ul. There is no BSA, preservative, or glycerol.

Please do not hesitate to contact us if you need an...

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Thank you for your email regarding ab95492. I can confirm that we sell this antibody is liquid format. Originally, each vial contains 300ug and is reconstituted in 500ul of distilled water. I hope this information will be useful for y

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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