Anti-Cytochrome b245 Light Chain antibody [44.1] (ab80896)

Overview

  • Product name
    Anti-Cytochrome b245 Light Chain antibody [44.1]
    See all Cytochrome b245 Light Chain primary antibodies
  • Description
    Mouse monoclonal [44.1] to Cytochrome b245 Light Chain
  • Specificity
    This antibody is specific for Human Cytochrome b245 Light Chain 29-TAGRF-33 & 183-PQVNPI-188.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (Human): Partially Purified human neutrophil flavocytochrome b (heparin Ultrogel/lectin affinity purification – in Triton X-100).

Properties

Applications

Our Abpromise guarantee covers the use of ab80896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.

Target

  • Relevance
    Cytochrome b245 Light Chain/p22phox is a critical component of the membrane-bound oxidase complex that generates superoxide. It complexes with NOX3 to form a functional NADPH oxidase.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • CYBA antibody
    • Cytochrome b 245 alpha polypeptide antibody
    • Cytochrome b 245 light chain antibody
    • Cytochrome b alpha polypeptide antibody
    • Cytochrome b(558) alpha chain antibody
    • Cytochrome b(558) alpha subunit antibody
    • Cytochrome b558 subunit alpha antibody
    • Flavocytochrome b 558 alpha polypeptide antibody
    • Neutrophil cytochrome b 22 kDa polypeptide antibody
    • p22 phagocyte B-cytochrome antibody
    • p22-phox antibody
    • p22phox antibody
    • Superoxide-generating NADPH oxidase light chain subunit antibody
    see all

Anti-Cytochrome b245 Light Chain antibody [44.1] images



  • Predicted band size : 21 kDa

    Western blot analysis of neutrophil p22phox, 44.1 expression in Human spleen using ab80896

References for Anti-Cytochrome b245 Light Chain antibody [44.1] (ab80896)

This product has been referenced in:
  • Ju HQ  et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun 8:14437 (2017). WB . Read more (PubMed: 28232723) »
  • Taylor RM & Jesaitis AJ Immunoaffinity purification of human phagocyte flavocytochrome b and analysis of conformational dynamics. Methods Mol Biol 412:429-37 (2007). Read more (PubMed: 18453126) »

See all 4 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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