Overview

  • Product name
    Anti-Cytochrome b5 antibody
    See all Cytochrome b5 primary antibodies
  • Description
    Rabbit polyclonal to Cytochrome b5
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 68-98 of Human Cytochrome b5 (NP_683725.1, NP_001905.1, NP_001177736.1).

  • Positive control
    • HepG2 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab116661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 15 kDa.

Target

  • Function
    Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
  • Involvement in disease
    Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.
  • Sequence similarities
    Belongs to the cytochrome b5 family.
    Contains 1 cytochrome b5 heme-binding domain.
  • Cellular localization
    Cytoplasm and Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CYB 5 antibody
    • CYB 5A antibody
    • CYB5 antibody
    • CYB5_HUMAN antibody
    • Cyb5a antibody
    • Cytochrome b 5 antibody
    • Cytochrome b5 (microsomal) antibody
    • Cytochrome b5 antibody
    • Cytochrome b5 type A (microsomal) antibody
    • Cytochrome b5 type A antibody
    • MCB 5 antibody
    • MCB5 antibody
    • Microsomal cytochrome b5 antibody
    • Microsomal cytochrome b5 type A antibody
    • Type 1 cyt b5 antibody
    see all

Images

  • Anti-Cytochrome b5 antibody (ab116661) at 1/100 dilution + HepG2 cell lysate at 35 µg

    Predicted band size : 15 kDa

References

ab116661 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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