Anti-Cytochrome P450 1A1 + 1A2 antibody [C10-7] (ab37130)

Overview

  • Product nameAnti-Cytochrome P450 1A1 + 1A2 antibody [C10-7]
    See all Cytochrome P450 1A1 + 1A2 primary antibodies
  • Description
    Mouse monoclonal [C10-7] to Cytochrome P450 1A1 + 1A2
  • Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Rainbow Trout
  • Immunogen

    Synthetic peptide corresponding to Cytochrome P450 1A1 + 1A2 aa 277-294.
    Sequence:

    SYDKDNIRDITDSLIDHC

  • Positive control
    • Liver microsomes from beta naphtoflavone treated (BNF) or tetrachlorodibenzo-p-dioxin (TCDD) treated fish.

Properties

Applications

Our Abpromise guarantee covers the use of ab37130 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
WB
IHC-P
  • Application notesELISA: 1/300 - 1/1000.
    IHC-P: Use at an assay dependent dilution. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol (see references).
    WB: 1/50 - 1/500. Predicted molecular weight: 55 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceCytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.
    • Cellular localizationEndoplasmic reticulum
    • Alternative names
      • Aryl hydrocarbon hydroxylase antibody
      • CP11 antibody
      • CP12 antibody
      • CYP1A1 antibody
      • CYP1A2 antibody
      • CYPIA1 antibody
      • CYPIA2 antibody
      • Cytochrome P450 family 1 subfamily A polypeptide 1 antibody
      • Cytochrome P450 family 1 subfamily A polypeptide 2 antibody
      • Cytochrome P450 subfamily I aromatic compound inducible polypeptide 1 antibody
      • Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2 antibody
      • P1 450 antibody
      • P3 450 antibody
      • P450 form 4 antibody
      • P450 form 6 antibody
      • P450 P1 antibody
      • P450 P3 antibody
      see all

    References for Anti-Cytochrome P450 1A1 + 1A2 antibody [C10-7] (ab37130)

    ab37130 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"