Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069)

Overview

  • Product nameAnti-Cytochrome P450 2A6 antibody [F16 P2 D8]
    See all Cytochrome P450 2A6 primary antibodies
  • Description
    Mouse monoclonal [F16 P2 D8] to Cytochrome P450 2A6
  • Tested applicationsSuitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the C-terminus of human CYP2A6 and conjugated to ovalbumin.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab56069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa).
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 1 µg/ml.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionExhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
  • Tissue specificityLiver.
  • Sequence similaritiesBelongs to the cytochrome P450 family.
  • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Coumarin 7 hydroxylase antibody
    • Coumarin 7-hydroxylase antibody
    • CP2A6_HUMAN antibody
    • CPA6 antibody
    • CYP2A antibody
    • CYP2A3 antibody
    • CYP2A6 antibody
    • CYPIIA6 antibody
    • Cytochrome P450 2A6 antibody
    • Cytochrome P450 IIA3 antibody
    • Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody
    • Cytochrome P450(I) antibody
    • Cytochrome P450, family 2 subfamily A polypeptide 6 antibody
    • Flavoprotein linked monooxygenase antibody
    • P450C2A antibody
    • P450PB antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] images

  • Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml

    Predicted band size : 57 kDa
    Observed band size : 54 kDa (why is the actual band size different from the predicted?)
  • This image shows normal human liver tissue stained by ab56069 at 1µg/ml.

References for Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069)

ab56069 has not yet been referenced specifically in any publications.

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