Anti-CYP2A6 antibody [F16 P2 D8] (ab56069)
Key features and details
- Mouse monoclonal [F16 P2 D8] to CYP2A6
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-CYP2A6 antibody [F16 P2 D8]
See all CYP2A6 primary antibodies -
Description
Mouse monoclonal [F16 P2 D8] to CYP2A6 -
Host species
Mouse -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human CYP2A6 (C terminal) conjugated to ovalbumin.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
F16 P2 D8 -
Myeloma
Ag8.653 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab56069 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa).
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IHC-P |
Use a concentration of 1 µg/ml.
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Notes |
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WB
Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa). |
IHC-P
Use a concentration of 1 µg/ml. |
Target
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Function
Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity. -
Tissue specificity
Liver. -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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Database links
- Entrez Gene: 1548 Human
- Omim: 122720 Human
- SwissProt: P11509 Human
- Unigene: 250615 Human
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Alternative names
- Coumarin 7 hydroxylase antibody
- Coumarin 7-hydroxylase antibody
- CP2A6_HUMAN antibody
see all
Images
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Anti-CYP2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml + Recombinant cytochrome p450
Predicted band size: 57 kDa
Observed band size: 54 kDa why is the actual band size different from the predicted? -
This image shows normal human liver tissue stained by ab56069 at 1µg/ml.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab56069 has been referenced in 1 publication.
- Dhamankar V et al. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhal Toxicol 27:767-77 (2015). PubMed: 26572092