Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069)

Overview

  • Product name
    Anti-Cytochrome P450 2A6 antibody [F16 P2 D8]
    See all Cytochrome P450 2A6 primary antibodies
  • Description
    Mouse monoclonal [F16 P2 D8] to Cytochrome P450 2A6
  • Tested applications
    Suitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from the C-terminus of human CYP2A6 and conjugated to ovalbumin.

Properties

Applications

Our Abpromise guarantee covers the use of ab56069 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa).
ELISA Use at an assay dependent concentration.
IHC-P Use a concentration of 1 µg/ml.
ICC/IF Use at an assay dependent concentration.

Target

  • Function
    Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
  • Tissue specificity
    Liver.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Coumarin 7 hydroxylase antibody
    • Coumarin 7-hydroxylase antibody
    • CP2A6_HUMAN antibody
    • CPA6 antibody
    • CYP2A antibody
    • CYP2A3 antibody
    • CYP2A6 antibody
    • CYPIIA6 antibody
    • Cytochrome P450 2A6 antibody
    • Cytochrome P450 IIA3 antibody
    • Cytochrome P450 subfamily IIA (phenobarbital inducible) polypeptide 6 antibody
    • Cytochrome P450(I) antibody
    • Cytochrome P450, family 2 subfamily A polypeptide 6 antibody
    • Flavoprotein linked monooxygenase antibody
    • P450C2A antibody
    • P450PB antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] images

  • Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml

    Predicted band size : 57 kDa
    Observed band size : 54 kDa (why is the actual band size different from the predicted?)
  • This image shows normal human liver tissue stained by ab56069 at 1µg/ml.

References for Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069)

ab56069 has not yet been referenced specifically in any publications.

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