Anti-Cytochrome p450 2C19 antibody (ab83233)

Overview

  • Product nameAnti-Cytochrome p450 2C19 antibody
    See all Cytochrome p450 2C19 primary antibodies
  • Description
    Rabbit polyclonal to Cytochrome p450 2C19
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, African Green Monkey
  • Immunogen

    Synthetic peptide corresponding to a region within the internal sequence amino acids 323-372 (QEEIERVIGR NRSPCMQDRG HMPYTDAVVH EVQRYIDLIP TSLPHAVTCD) of Human Cytochrome p450 2C19 (NP_000760).

  • Positive control
    • Placental lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab83233 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionResponsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine.
  • Sequence similaritiesBelongs to the cytochrome P450 family.
  • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • (R)-limonene 6-monooxygenase antibody
    • (S)-limonene 6-monooxygenase antibody
    • (S)-limonene 7-monooxygenase antibody
    • CP2CJ_HUMAN antibody
    • CPCJ antibody
    • CYP2C antibody
    • CYP2C19 antibody
    • CYPIIC17 antibody
    • CYPIIC19 antibody
    • Cytochrome P-450 II C antibody
    • Cytochrome P450 2C19 antibody
    • Cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 antibody
    • Cytochrome P450-11A antibody
    • Cytochrome P450-254C antibody
    • Flavoprotein-linked monooxygenase antibody
    • Mephenytoin 4 hydroxylase antibody
    • Mephenytoin 4-hydroxylase antibody
    • Microsomal monooxygenase antibody
    • P450-11A antibody
    • P45011A antibody
    • P450C2C antibody
    • S-mephenytoin 4-hydroxylase antibody
    • Xenobiotic monooxygenase antibody
    see all

Anti-Cytochrome p450 2C19 antibody images

  • Anti-Cytochrome p450 2C19 antibody (ab83233) at 1 µg/ml + placental lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

References for Anti-Cytochrome p450 2C19 antibody (ab83233)

ab83233 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Loading amount 25 µg
Gel Running Conditions Non-reduced Denaturing (8% gel)
Sample Pig Cell lysate - whole cell (endothelial cell)
Specification endothelial cell
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 20°C
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Submitted Dec 05 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"