Anti-Cytochrome P450 2C9 antibody (ab80213)

Overview

  • Product name
    Anti-Cytochrome P450 2C9 antibody
    See all Cytochrome P450 2C9 primary antibodies
  • Description
    Rabbit polyclonal to Cytochrome P450 2C9
  • Tested applications
    Suitable for: IHC-P, WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (Human) conjugated to KLH from the center region

  • Positive control
    • CEM cell line lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab80213 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50.
WB 1/50 - 1/100. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
ELISA 1/1000.

Target

  • Function
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • (R)-limonene 6-monooxygenase antibody
    • (S)-limonene 6-monooxygenase antibody
    • (S)-limonene 7-monooxygenase antibody
    • CP2C9_HUMAN antibody
    • CPC9 antibody
    • CYP2C antibody
    • CYP2C10 antibody
    • CYP2C9 antibody
    • CYPIIC9 antibody
    • cytochrome P-450 S-mephenytoin 4-hydroxylase antibody
    • Cytochrome P-450MP antibody
    • Cytochrome P450 2C9 antibody
    • Cytochrome P450 MP-4 antibody
    • Cytochrome P450 MP-8 antibody
    • Cytochrome P450 PB-1 antibody
    • Cytochrome P450, family 2, subfamily C, polypeptide 9 antibody
    • Cytochrome p4502C9 antibody
    • flavoprotein-linked monooxygenase antibody
    • MGC149605 antibody
    • MGC88320 antibody
    • microsomal monooxygenase antibody
    • OTTHUMP00000020135 antibody
    • P450 MP antibody
    • P450 PB 1 antibody
    • P450 PB1 antibody
    • P450IIC9 antibody
    • P450MP antibody
    • S mephenytoin 4 hydroxylase antibody
    • S-mephenytoin 4-hydroxylase antibody
    • xenobiotic monooxygenase antibody
    see all

Images

  • Anti-Cytochrome P450 2C9 antibody (ab80213) at 1/50 dilution + CEM cell line lysate at 35 µg

    Predicted band size : 56 kDa
    Observed band size : 56 kDa
    Additional bands at : 130 kDa. We are unsure as to the identity of these extra bands.
  • ab80213 at 1/50 dilution staining Cytochrome P450 2C9 in human hepatocarcinoma tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A peroxidase conjugated secondary antibody was used followed by DAB staining.

References

ab80213 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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