Anti-Cytochrome P450 2E1 antibody (ab106799)

Overview

  • Product name
    Anti-Cytochrome P450 2E1 antibody
    See all Cytochrome P450 2E1 primary antibodies
  • Description
    Goat polyclonal to Cytochrome P450 2E1
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide:

    RKVIKNVAEVK

    by a Cysteine residue linker, corresponding to internal sequence amino acids 233-243 of Human Cytochrome P450 2E1 (NP_000764.1)

  • Positive control
    • Human Liver lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab106799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.02 - 0.5 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 57 kDa).
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 4-nitrophenol 2-hydroxylase antibody
    • CP2E1_HUMAN antibody
    • CPE1 antibody
    • CYP2E antibody
    • Cyp2e1 antibody
    • CYPIIE1 antibody
    • Cytochrome P450 2E1 antibody
    • Cytochrome P450 isozyme 3A antibody
    • Cytochrome P450 LM3A antibody
    • Cytochrome P450, family 2, subfamily e, polypeptide 1 antibody
    • cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 antibody
    • Cytochrome P450, subfamily IIE antibody
    • Cytochrome P450-ALC antibody
    • Cytochrome P450-J antibody
    • Cytochrome P450RLM6 antibody
    • EC 1.14.13.- antibody
    • EC 1.14.13.n7 antibody
    • Ethanol-inducible P450 antibody
    • Flavoprotein-linked monooxygenase antibody
    • MGC133529 antibody
    • Microsomal monooxygenase antibody
    • OTTHUMP00000020813 antibody
    • OTTHUMP00000046571 antibody
    • P450 ALC antibody
    • P450-J antibody
    • P450C2E antibody
    • P450J antibody
    • P450RLM6 antibody
    • Xenobiotic monooxygenase antibody
    see all

Images

  • Anti-Cytochrome P450 2E1 antibody (ab106799) at 0.05 µg/ml + Human Liver lysate at 35 µg

    Predicted band size : 57 kDa
  • ab106799 (3.8µg/ml) staining of paraffin embedded Human Liver shows ER-like staining in hepatocytes. Tissue treated as follows: Steamed antigen retrieval with citrate buffer pH 6 and decection using AP-staining.

References

ab106799 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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