General notesab94254 is a 293T cell transfected lysate in which Human Cytochrome P450 2E1 has been transiently over-expressed using a pCMV-Cytochrome P450 2E1 plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more detailed how the transfected lysate was prepared view preparation notes
BackgroundFunction: Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
Similarity: Belongs to the cytochrome P450 family.