The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/50 - 1/100. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).
FunctionThis enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. One of the predominant enzymes responsible for the epoxidation of endogenous cardiac arachidonic acid pools.
Tissue specificityHighly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.
Sequence similaritiesBelongs to the cytochrome P450 family.