Overview

  • Product nameAnti-Cytochrome P450 3A5 antibody
    See all Cytochrome P450 3A5 primary antibodies
  • Description
    Rabbit polyclonal to Cytochrome P450 3A5
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Does not react with: Rat
  • Immunogen

    Synthetic hexapeptide including the C-terminal of human Cytochrome P450 3A5, conjugated to keyhole limpet haemocyanin using a maleimido linkage.

  • Positive control
    • Human liver microsomal preparations.

Properties

Applications

Our Abpromise guarantee covers the use of ab22692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/2000. Predicted molecular weight: 57 kDa.

    Note: dilute ab22692 to working concentration with 50mM Tris-HCl buffer (pH 7.6) containing 1.5% sodium chloride and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
    • Sequence similaritiesBelongs to the cytochrome P450 family.
    • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Aryl hydrocarbon hydroxylase antibody
      • CP35 antibody
      • CP3A5_HUMAN antibody
      • CYP3A5 antibody
      • CYPIIIA5 antibody
      • Cytochrome P450 3A5 antibody
      • Cytochrome P450 antibody
      • Cytochrome P450 family 3 subfamily A polypeptide 5 antibody
      • Cytochrome P450 HLp2 antibody
      • Cytochrome P450 subfamily IIIA (niphedipine oxidase) polypeptide 5 antibody
      • Cytochrome P450-PCN3 antibody
      • DKFZp686L16231 antibody
      • Flavoprotein linked monooxygenase antibody
      • FLJ31317 antibody
      • HLp2 antibody
      • Microsomal monooxygenase antibody
      • Niphedipine oxidase antibody
      • P450PCN3 antibody
      • PCN3 antibody
      • Xenobiotic monooxygenase antibody
      see all

    References for Anti-Cytochrome P450 3A5 antibody (ab22692)

    This product has been referenced in:
    • Leskelä S  et al. Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer. Endocr Relat Cancer 14:645-54 (2007). Read more (PubMed: 17914095) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"