Overview

  • Product nameAnti-Cytohesin 2 antibody
    See all Cytohesin 2 primary antibodies
  • Description
    Goat polyclonal to Cytohesin 2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Rat, Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Synthetic peptide:

    EDGVYEPPDLTP

    , from the N-terminus of human Cytohesin 2

  • Positive control
    • Human cerebellum and rat brain lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab65945 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 46 kDa).

    Peptide ELISA: antibody detection limit dilution 1:32,000.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.
    • Tissue specificityUbiquitous.
    • Sequence similaritiesContains 1 PH domain.
      Contains 1 SEC7 domain.
    • DomainThe PH domain is necessary and sufficient for plasma membrane relocalization.
    • Cellular localizationCell membrane. Cytoplasm. Both isoform 1 and isoform 2 are recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. Requires also interaction with phosphoinositides for targeting to plasma membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARF exchange factor antibody
      • ARF nucleotide binding site opener antibody
      • ARF nucleotide-binding site opener antibody
      • Arno antibody
      • ARNO protein antibody
      • CLM2 antibody
      • CTS18 antibody
      • CTS18.1 antibody
      • CYH2_HUMAN antibody
      • Cyth2 antibody
      • Cytohesin 2 antibody
      • Cytohesin-2 antibody
      • MGC137537 antibody
      • MGC80440 antibody
      • PH antibody
      • PH, SEC7 and coiled-coil domain-containing protein 2 antibody
      • Pleckstrin homology Sec7 and coiled coil domains 2 antibody
      • Pleckstrin homology Sec7 and coiled coil domains protein 2 antibody
      • Protein ARNO antibody
      • PSCD2 antibody
      • PSCD2L antibody
      • PSCD2L, formerly antibody
      • SEC7 and coiled-coil domain-containing protein 2 antibody
      • Sec7 antibody
      • SEC7 homolog B antibody
      • Sec7B antibody
      • SEC7L antibody
      • Sec7p L antibody
      • Sec7p-like antibody
      • Sec7pL antibody
      see all

    Anti-Cytohesin 2 antibody images

    References for Anti-Cytohesin 2 antibody (ab65945)

    ab65945 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab65945.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"