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Overview
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Product nameAnti-Cytokeratin 13 antibody - C-terminal
See all Cytokeratin 13 primary antibodies -
DescriptionGoat polyclonal to Cytokeratin 13 - C-terminal
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Host speciesGoat
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Specificityab188874 is expected to recognize the reported isoform a (NP_002265.2) only.
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Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
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Species reactivityReacts with: Human
Predicted to work with: Monkey, Gorilla
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Immunogen
Synthetic peptide corresponding to Human Cytokeratin 13 aa 444-458 (C terminal) (Cysteine residue).
Sequence:TSNASGRRTSDVRRP
Database link: P13646 -
Positive control
- Human lung lysate and human tonsil tissue.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Related Products
Applications
Our Abpromise guarantee covers the use of ab188874 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | Use a concentration of 0.1 - 0.3 µg/ml. | |
| WB | Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 50 kDa. | |
| IHC-P | Use a concentration of 2.5 µg/ml. |
Target
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Tissue specificityExpressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
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Involvement in diseaseDefects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
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Sequence similaritiesBelongs to the intermediate filament family.
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Post-translational
modificationsO-glycosylated; glycans consist of single N-acetylglucosamine residues. - Information by UniProt
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Database links
- Entrez Gene: 101146156 Gorilla
- Entrez Gene: 3860 Human
- Omim: 148065 Human
- SwissProt: P13646 Human
- Unigene: 654550 Human
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Alternative names
- 47 kDa cytokeratin antibody
- CK-13 antibody
- CK13 antibody
see all
Images
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Western blot - Anti-Cytokeratin 13 antibody - C-terminal (ab188874)Anti-Cytokeratin 13 antibody - C-terminal (ab188874) at 0.1 µg/ml + Human lung lysate (in RIPA buffer) at 35 µg
Predicted band size: 50 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 13 antibody - C-terminal (ab188874)Immunohistochemical analysis of paraffin embedded human tonsil tissue labeling Cytokeratin 13 with ab188874 at 2.5 µg/ml.
References
ab188874 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"